March 1, 2023 Dr. Bruce Blackwell

Difference Between Tapentadol and Tramadol

The doctor generally prescribes two types of medication to relieve pain. These medications can be opioids or non-opioids.

In this article, you will learn about two mainly prescribed opioid drugs.

Tapentadol and Tramadol belong to a class of medicines known as Opioids. But the main thing to note about them is that they work differently. Tapentadol is a potent opioid drug used for moderate to severe pain in musculoskeletal disorders. Whereas, Tramadol is a weaker opioid that helps to relieve mild to moderate pain.

According to a review published in 2021, Tapentadol is two to three times more potent than Tramadol.

The review shows both drugs' Pharmacological, Efficacy, and Safety Profiles on adult patients.

Both drugs are found to be sharing similar mechanisms of action during their medical therapies. They both contain mu-agonist and monoaminergic properties. But, the potency of Tapentadol is roughly two to three times greater than that of Tramadol. And less potent by two to three times than morphine.

The toxicity of Tramadol and Tapentadol is usually found to be similar.

However, Tapentadol is more likely to result in less exposure to serotoninergic side effects. Symptoms such as nausea, hypoglycemia, and vomiting are among these side effects.

But Tapentadol may cause more opioid adverse effects as compared to Tramadol. It may cause adverse opioid effects such as constipation, respiratory depression, and addiction.

Is Tapentadol as Tramadol?

Tapentadol is not the same as Tramadol; it's a more potent opioid medication than Tramadol.

The doctor usually prescribes it for moderate to severe pain. Its effects stay longer than Tramadol, which is more effective in managing pain.

Both drugs may cause side effects during their use, but they rarely appear in people.

They may cause symptoms like constipation, nausea, headache, dizziness, and vomiting. Tapentadol in higher doses or long-term use may lead to the potential risk of seizures and serotonin syndrome. Also, it may form an addiction, so one should use it cautiously and only as prescribed.

Learn More - Long-Term Side Effects of Tapentadol

Compared to Tramadol, Tapentadol is not considered an opioid replacement treatment. Tramadol may help kick the habit of other opioids in a person. Tapentadol may also cause respiratory depression and muscle spasms in some cases.

It is essential to talk with a doctor if any side effects appear during the use of these drugs. Take safety measure the prevent risk factors.

Avoid the use of alcohol with Tapentadol or with drugs that affect the central nervous system, such as benzodiazepines.

You can take Tramadol with certain other medicines but use them cautiously. Ask your doctor before you take any medicine with these opioid medications.

Can you mix Tapentadol with Tramadol?

It would be best not to mix Tapentadol with Tramadol; using them together may increase the risk of side effects. Also, the combined use may lead to dangerous drug interactions. Please consult a doctor first if you need to take both medicines.

Does Tapentadol make you sleepy?

Yes, Tapentadol can make you feel tired or sleepy during its use.

If you experience these effects of the drug on yourself, please be cautious. Avoid activities that need alertness and avoid driving or operating machinery. Wait until you get back into normal condition.

In conclusion, Tapentadol and Tramadol are Both examples of opioid medications. Tapentadol, compared to Tramadol, is more potent and used for moderate to severe pain. But, potential Tapendtadol has more side effects than Tramadol, so caution is essential during its use. You must consult a doctor and know which medicine will be best for you.

Visit us - To Buy Generic Tapentadol Aspadol

Remember, as opioid medications, both drugs can be addictive. You should take these drugs only when a doctor approves their use. Both drugs are effective in managing pain at their levels.

Reference Link for the Review
Tapentadol Versus Tramadol: A Narrative and Comparative Review of Their Pharmacological, Efficacy and Safety Profiles in Adult Patients